Seyed Mousal-Reza Hosseini; Gholam Reza Ghayour Razmgah; Mohsen Nematy; Habibollah Esmaily; Mahdi Yousefi; Mohammad Kamalinejad; Seyed Hamdollah Mosavat
Volume 20, Issue 3 , 2018, Pages 1-8
Abstract
Background: There are several therapeutic strategies available from the viewpoint of Traditional Persian Medicine (TPM) to treat hepatic diseases. Objectives: This study aimed at assessing the efficacy and safety of Nigella sativa and Melissa officinalis in patients with Non-Alcoholic Fatty Liver Disease ...
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Background: There are several therapeutic strategies available from the viewpoint of Traditional Persian Medicine (TPM) to treat hepatic diseases. Objectives: This study aimed at assessing the efficacy and safety of Nigella sativa and Melissa officinalis in patients with Non-Alcoholic Fatty Liver Disease (NAFLD). Methods: From November 2014 to May 2016, in an open-label, simple-blocked, randomized controlled clinical trial, the researchers evaluated the efficacy of Nigella sativa and Melissa officinalis compared with Orlistat capsule on the grade of fatty liver and the serumlevels of Aspartate Transaminase (AST) and Alanine Transaminase (ALT) in 50 patients with NAFLD in Iran. Results: Regarding within-group changes, a significant decrease was observed in the serum level of AST, ALT, body mass index, and grade of fatty liver in both groups after the intervention compared with baseline (P < 0.001). Repeated measures logistic regression analysis showed that there was a more significant reduction in the grade of fatty liver over the study period in the intervention group compared with the control group (0.58 ± 0.50 versus 1.51 ± 0.54, P < 0.001).Conclusion: Traditional Persian Medicine-based preparations of Nigella sativa and Melissa officinalis could reduce body weight and liver enzymes and improves the grade of fatty liver in Non-Alcoholic Fatty Liver Disease
Sedigheh Sedigh Mobarakabadi; Khadijeh Mirzaie Najmabadi; Mahmoud Ghazi Tabatabaie; Habibollah Esmaily
Volume 19, Issue 2 , February 2017, , Pages 1-8
Abstract
Background: Although there are studies that suggest a vast expansion of medicalization of pregnancy and birth in Iran, data about the rate of intervention applications caused by the medicalization in low-risk pregnancies and birth is limited. Moreover, there is limited information on the effectiveness ...
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Background: Although there are studies that suggest a vast expansion of medicalization of pregnancy and birth in Iran, data about the rate of intervention applications caused by the medicalization in low-risk pregnancies and birth is limited. Moreover, there is limited information on the effectiveness of these interventions for different modes of childbirth.Objectives: This study aimed to determine the rate of application of maternal medicalized care in low-risk pregnancies and births and to identify the factors that are associated with type of delivery.Patients and Methods: This cross-sectional study was performed by stratified-cluster sampling on 320 postpartum women from four public and private hospitals in Mashhad, Iran. The data collection instrument was a designed and standardized tool for assessment of medicalized pregnancy and childbirth. Also, descriptive tests and logistic regression were used. A value of P < 0.05 was considered statistically significant for all tests.Results: In this study, the rates of natural vaginal and caesarean birth were 34.7% and 65.3%, respectively. Preconception and prenatal care received from an obstetrician were 72.8% and 51.6%, respectively. Themedian number of prenatal visits, laboratory examinations and sonography procedures was 12, 3 and 4, respectively. In 49.4% of the cases, the women were hospitalized before the onset of labor. Early admission (OR = 2.40; 95% CI = 1.93 - 2.97; P = 0.001) and performing electronic fetal heart monitoring during admission (OR = 2.47; 95% CI = 1.28 - 4.73; P = 0.006) were the interventions that the regression logistic analysis identified as associated with a higher rate of caesarean delivery.Conclusions: It seems that obstetric interventions are widely applied in low-risk pregnancies and births. Some of these interventions have the effect of increasing the rate of caesarean delivery. According to the provided information, it seems that it is necessary to adjust health policy to provide appropriate care for low-risk pregnancies and births.
